Haemodynamically significant patent ductus arterious in preterm infants / 国际儿科学杂志

ABSTRACT

Patent ductus arteriosus (PDA) is a common disease in prcterm infants,and haemodynamically significant patent ductus arteriosus (hsPDA) has a serious impact on mortality and disability of the premature infants.hsPDA is a complex pathophysiological process involving multiple factors.Clinical symptoms and signs are not specific,and there is no uniform standard for identifying hsPDA.Clinical manifestations combined with echocardiography and biomarkers are important means to diagnose the hsPDA.The treatment of hsPDA for premature infants includes supportive treatment,drug therapy,surgical ligation and transcatheter interventional therapy.This article reviews the research progress of hsPDA in premature infants.