Clinical study of Wuwei-Xiaodu decoction lavage assisted vacuum sealing drainage (VSD)in the treatment of perianal abscess pus period / 国际中医中药杂志

ABSTRACT

Objective To evaluate the clinical effect of Wuwei-Xiaodu decoction lavage assisted VSD in the treatment of perianal abscess pus period. Methods Ninety patients with perianal abscess who met the inclusion criteria were divided into 2 groups by random number table, 45 in each group. The control group was treated with 0.9％ sodium chloride injection assisted VSD. The treatment group was treated with Wuwei-Xiaodu decoction lavage assisted VSD treatment. Both groups were treated for 7 days. WBC was detected by automatic hemorheology tester, CRP, IL-6 and TNF-α were detected by ELISA. The anus bulge, anal self-made function, wound exudation, wound pain were scored and the incision bacteria were detected after treatment. The rate and number of colonies were evaluated. Results The total effective rate was 88.89％ (40/45) in the treatment group and 73.33％ (33/45) in the control group. The total effective rate of the two groups was statistically significant (Z=-2.584, P=0.010). After treatment, the levels of WBC, CRP, IL-6, and TNF-α in the treatment group were significantly lower than those in the control group (t=-3.730, -2.385, -2.170, -3.509, P=0.007, 0.023, 0.034, 0.011). The anal bulge, wound exudation, and wound pain scores in the treatment group were significantly lower than those in the control group (t=-2.760, -2.549, -21.151, P=0.005, 0.017, 0.038),. The rate of incision bacteria was significantly lower than that in the control group (χ2=4.406, P=0.036), the number of colonies were significantly lower than that of the control group (t=5.375, P<0.01). Conclusions The Wuwei-Xiaodu decoction lavage assisted VSD can effectively reduce the number of colonies in the perianal period of patients with perianal abscess, reduce postoperative anal bulge, pain and wound exudation, and improve clinical efficacy.