Risk factors of extrapulmonary complications after Mycoplasma pneumoniae pneumonia / 中华实用儿科临床杂志

ABSTRACT

Objective To identify the risk factors of extrapulmonary complications in children with Mycoplasma pneumoniae pneumonia (MPP),in order to provide evidence for the correct clinical diagnosis and effective treatment to reduce the incidence of extrapulmonary complications.Methods The clinical data of 234 hospitalized children with MPP from Jan.2008 to Jan.2010 were retrospectively reviewed.Based on the findings of extrapulmonary complications,the subjects were divided into 2 groupsthe extrapulmonary complications group (107 cases) and non-extrapulmonary complications group (127 cases).The comparison was made between the 2 groups in age,gender,fever,the manifestation of pneumonia on X-ray or CT scan,white blood cell count,erythrocyte sedimentation rate (ESR),C reaction protein (CRP) and application of macrolide medicine etc.Results All the systems were involved in extrapulmonary complications,the most 2 involved systems were circulatory system and digestive system,ranking 11.1 1％ and 10.68％ respectively.The other involved systems were the blood system(8.12％),skin (5.56％),urinary (1.71％),and nervous system (2.14％),11 cases (4.70％)had two or more organ damages.The results of analysis indicated that the related risk factors included CRP(P ＜ 0.05),ESR(P ＜ 0.05),lung patchy shadow(P ＜ 0.01)and application of macrolide medicine more than 7 days of sickness(P ＜0.01).But there was no significant difference between the 2 groups in age,gender,fever,pleural effusion,white blood cell count (all P ＞ 0.05).Conclusions Extrapulmonary complications with MPP can be involved in every system.In severe cases,multi-system organ can be suffered.CRP,ESR,lung patchy shadow and application of Macrolide medicine within 7 days of sickness are factors associated with extrapulmonary complications.