Changes of serum iron and serum ferritin in children with vasovagal syncope / 中华实用儿科临床杂志

ABSTRACT

Objective To explore the changes of serum iron (SI)level and serum ferritin (SF) level in children with vasovagal syncope(VVS).Methods Twenty-one children [12 male,9 famel,8-14 years old,mean(11.71 ±2.31) years old] were enrolled in this study,who came from children syncope out-patient department or in-patient department of the Second Xiangya Hospital of Central South University from May 2011 to Apr.2012,complaining of syncope or pre-syncope symptoms and turned out to be head-up tilt testing(HUTF) positive,compared with 18 healthy children(healthy control group).All the children were taken blood in the early morning with empty stomach to measure blood SI,SF,hemoglobin(Hb),hematocrit value(Hct) and average red blood cell volume(MCV).The SPSS 16.0 software was used for statistical analysis.Results 1.Age and gender differences were found no statistical significance in syncope group and healthy control group(all P ＞ 0.05).2.SI level in syncope group was lower than that in healthy control group [(15.15 ± 4.55) μmol/L vs (18.24 ± 4.15) μmol/L,P ＜ 0.05].SF level in syncope group was lower than that in healthy control group [(59.10 ± 26.81) μg/L vs (79.83 ± 33.58) μg/L,P ＜ 0.05].Hct level in syncope group was higher than that in healthy control group [(40.19 ± 3.44) ％ vs (38.01 ± 2.68) ％,P ＜ 0.05].3.Gender compare in syncope groupthere were no statistical difference in SI,SF,Hct,MCV and Hb between male and female vasovagal syncope patients(all P ＞ 0.05).4.There were no statistically significant differences in SI,SF,Hb,Hct and MCV between recurrent syncope and accidental syncope (all P ＞ 0.05).Conclusions SI,SF level reduce in VVS children,and there was no gender difference.