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Clinical analysis of congenital heart disease with pulmonary arterial hypertension in 119 cases / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics ; (24): 997-999, 2013.
Article in Chinese | WPRIM | ID: wpr-733089
ABSTRACT
Objective To conduct a retrospective study on 119 cases and followed-up in order to improve the therapeutic efficacy of congenital heart disease(CHD) with pulmonary arterial hypertension(PAH).Methods Totally 119 cases of CHD with PAH were collected from Jan.2005 to Dec.2010.The information included the clinical data and relevant auxiliary examinations.The ages varied from 1 month to 15 years old,and the average age was (42.4 ± 2.8) months.They were treated with drugs,interventional therapy or surgical treatment.Regular follow-up monitored the symptom,sign and the auxiliary examination including chest X ray and echocardiography.Results There were 66 children who had been treated with cardiac catheterization and 1 case had hemolysis 1 day after the catheterization,but finally all of them were cured.There were 53 cases who received surgical operation and 49 cases were improved.After the operation,1 case became complicated with infection of incision wound,8 cases had upper respiratory infection,8 cases had arrhythmia,and 1 case complicated with pneumonia.Four cases died because of low cardiac output syndrome and pulmonary hypertension articulo.After the treatment,the pulmonary artery pressure came to the scope within from 8 to 90 mm Hg[(20.23 ± 7.13) mm Hg],which showed a significant statistic difference compared to before (t =3.812,P < 0.01),and there were 79 cases (66.4%) whose pulmonary pressure decreased > 40 mm Hg.There were 17 cases of severe PAH,who received surgical operation after the drug treatment.There were 14 cases(82%) whose pulmonary artery pressure decreased > 20 mm Hg.There were 2 cases had low cardiac output syndrome,and 1 case had PAH articulo.After the therapy,the pulmonary arterial pressure,cardiac thoracic ratio,chambers size,the systolic function of left heart were all improved compared with before.Conclusions It is important to diagnose as early as possible the CHD children with PAH,and to choose proper time for interventional or surgical therapy,especially for the moderate and severe cases,so that the cure rate as well as survival quality can be improved.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study Language: Chinese Journal: Chinese Journal of Applied Clinical Pediatrics Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study Language: Chinese Journal: Chinese Journal of Applied Clinical Pediatrics Year: 2013 Type: Article