Analysis of the difference of risk factors between each stage of necrotizing enterocolitis / 中华实用儿科临床杂志

ABSTRACT

Objective To discuss the differences of the risk factors between Bell Stage Ⅰ and Stage Ⅱ/Ⅲ of neonatal necrotizing enterocolitis (NEC),in order to provide theoretical basis for better preventing and treating NEC of each stages.Methods Eighty seven NEC neonates'references from 2009 to 2011 were all analyzed retrospectively to find out relative risk factors.They were divided into 2 groups according to Bell stagestage Ⅰ and stage Ⅱ/Ⅲ.Twenty four items were compared between the 2 groups,including perinatal factors,feeding methods,complications,RBC perfusion,etc,using SPSS 17.0 software to make single factor analysis,for the sake of finding out relative risk factors.Results The comparison of gestational age,birth weight,onset age,and onset weight between 2 groups has no statistical significance (P ＞ 0.05).The mortality of stage Ⅱ / Ⅲ was higher than stage Ⅰ (P ＜ 0.05).Seven of 24 items have statistical difference in the comparison (P ＜ 0.05),includingGestational diabetes mellitus,amniotic fluid disorders,respiratory failure,hypothyroid,anemia,sepsis,RBC perfusion,indicating that these items may correlate to incidence and severity of NEC.Conclusions Gestational diabetes mellitus,amniotic fluid disorders,respiratory failure,hypothyroid,anemia,sepsis,RBC perfusion are risk factors that influence the severity of NEC.