Investigation of childhood asthma morbidity rate and risk factors in Wuhan area / 中华实用儿科临床杂志

ABSTRACT

Objective To investigate the relative risk factors of childhood asthma.Methods An investigation was carried out by random sampling in Wuhan city.The investigation included questionnaire and clinic examination.The studied atients were the infants and children aged from 0 to 14 years old,and the sample size was of 4132 cases.The relative analysis between childhood asthma and other allergic diseases was carried out,and high risk factors were screened by multiple Logistic regression analysis with SPSS 17.0 software.Results There were 173 children with asthma,and the accumulation incidence rate was 4.2％,during which the rate of male children were higher than that of female children (4.8％ vs 3.6％).Four years old was a key point,because the incidence rates of allergic rhinitis,eczema,drug allergy and food allergy were obviously increased after this point.The relative analysis results showed that allergic rhinitis was the first factor related to asthma (r =0.30,P ＜ 0.01),the second factor was eczema (r =0.24,P ＜ 0.01).The multiple Logistic regression analysis results showed that the risk factors of asthma were listed by risk degree as allergic rhinitis (OR =5.61,95％ CI3.88-8.13),repeated respiratory infection (OR =3.99,95％ CI2.78-5.74),eczema (OR =3.38,95 ％ CI2.35-4.87),drug allergy (OR =2.20,95 ％ CI1.44-3.36),asthma history of the first degree relative (OR =3.14,95％ CI1.60-6.13) and asthma history of the second degree relative (OR =1.92,95％ CI1.13-3.28).Conclusions Allergic rhinitis and repeated respiratory infection are the first and the second important risk factors of asthma.It is necessary to enhance the health management of the related children to prevent them from developing asthma.