Detection of Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila in children with acute respiratory infection / 中华实用儿科临床杂志

ABSTRACT

Objective To analyze the characteristics of Mycoplasma pneumo-niae (MP),Chlamydia pneumoniae (CP),Legionella pneumophila (LP) in hospitalized children with acute respiratory tract infection.Methods Serum and urine were collected from 5275 children (aged from 3 days to 16 years old) admitted with acute respiratory tract infection from Jan.to Dce.2012.The levels of MP-IgM,CP-IgM in serum,and LP antigen in urine were detected by passive agglutination,enzyme-linked immunosorbent assay,and immunochromatographic assay respectively.The epidemiology of positive cases were analyzed.Results 1.Among 5275 children with acute respiratory tract infection,1537 cases (29.1％) were detected with at least 1 type of the pathogensMP infection was 20.1％ (1060 cases),CP infection was 8.7％ (45 cases),and LP positive rate was 0.3％ (18 cases),mix infection rate was 2.56％ (135 cases).2.The prevalence of MP,CP and LP infections in the different months and quarters were significantly different(all P ＜0.01).The positive rate of MP was highest in November while it was lowest in May.The positive rate of CP was highest in November while it was lowest in July.The positive rate of LP was highest in December,no infection case was found in February,May and the time during July to November.3.In all,the occurrence of positive results of MP,CP,and LP in children were higher in winter than that in other seasons.The infection of December was more than that in the other month.Meanwhile,infection of MP,CP and LP were mostly occured in children over age of 5.In addition,the positive rates were higher in male than that in female.Furthermore,children with bronchial pneumonia had higher positive rates of infection compared to children with acute respiratory tract infection.Conclusion Pathogen detection is an important basis for the diagnosis of children with the infection of MP,CP,LP.