Study on the effects of oral hypotensive compliance in elderly patients with frailty syndrome / 中国实用护理杂志

ABSTRACT

Objective To investigate the relationship between elderly hypertension patients with frailty syndrome and oral medication compliance. Methods Two hundred elderly patients with hypertensionwho visited the department of cardiology of the First Hospital Affiliated to Dalian Medical University from March 2015 to March 2017were randomly selected. General information was recorded for each patient. The Tilburg Frailty Indicator (TFI), Healthy behavior inventory (HBI) and medication adherence inventory (mmas-8) were assessed for each patient. The population variable and TFI were taken as independent variables, and the mmas-8 score and HBI score were taken as dependent variables to evaluate the linear correlation between each independent variable and each dependent variable. The above independent variables were used as covariates and the results were corrected by disordered multiple Logistic regression analysis. Results The average age of 200 patients was (73.5 ± 7.5) years old, including 103 women (51.5％, 103/200), 97 males (48.5％, 97/200), and the average medical history of hypertension was (12.5 ± 6.1) years. There were 74 patients (37％, 74/200) and 126 patients (63％, 126/200). The mean TFI was 4.3 ± 3.0. The average scores of physical, psychological and social factors were 7.6±3.1, 3.9±2.0, 1.4±0.9, and the average HBI was 3.3±0.3. Among them, the average scores of healthy eating habits, preventive health care, positive mentality and healthy behavior were 3.3±0.8, 3.3±0.4, 3.4± 0.5, and 3.4 ± 0.5, respectively. The mean MMAS-8 was 5.2 ± 2.0, with 144 patients (72％, 144/200) with low compliance and 38 (19％, 38/200) with moderate compliance. Age (Rho- 0.443), history of hypertension (r-0.421), TFI score (Rho-0.483) were negatively correlated with drug adherence (P<0.05). Married/cohabiting patients (tau_b 0.293), education level (tau_b0.391), monthly income (tau_b 0.398) were positively correlated with drug compliance, and the latter two were significantly positively correlated with drug compliance (P<0.01). Monthly income (tau_b0.371) was significantly positively correlated with HBI, and TFI score (Rho-0.364) were significantly negatively correlated with HBI, P<0.01. Logistic regression analysis suggested that education degree was a positive determinant of drug compliance (mmas-8) (B=0.81,P=0.01), and monthly income was a positive determinant of health behavior (HBI). Frailty syndrome (TFI) is a negative determinant of poor drug adherence (B=-0.11, P<0.01) and poor health behavior (B=-0.71, P=0.03). Conclusions Frailty syndrome is an important independent factor in predicting drug adherence and adherence to healthy behaviors. High education level improves patient compliance, and good financial status can make patients more active in adherence to healthy behaviors.