Therapeutic effect and safety of oral musk Baoxin pill in patients with stable angina pectoris of coro-nary heart disease / 心血管康复医学杂志

ABSTRACT

Objective:To explore therapeutic effect and safety of oral musk Baoxin pill in patients with stable angina pectoris (SAP) of coronary heart disease (CHD).Methods:A total of 158 SAP patients of CHD treated in our hos-pital were selected,and were randomly divided into routine treatment group (n＝79) and musk Baoxin pill group (n＝79,received musk Baoxin pill based on routine treatment ),both groups were treated for eight weeks.Therapeutic effect and safety were compared between two groups.Results:After treatment,there was no significant difference in total effective rate of ECG improvement between two groups,P＝0.475.Compared with routine treatment group after treatment,there were significant reductions in onset times of angina pectoris [(1.68 ± 0.43) times/d vs.(1.12 ± 0.37) times/d] and nitroglycerin consumption [(1.65 ± 0.87)/d vs.(1.08 ± 0.47)/d],and significant rise in to-tal effective rate of angina pectoris improvement (81.01% vs.96.20%) in musk Baoxin pill group,P＝0.001 all.No obvious adverse reactions occurred in two groups.Conclusion:Oral musk Baoxin pill based on routine treatment can significantly relieve angina pectoris symptoms and the safety is good in patients with stable angina pectoris of coronary heart disease.