Relationship of mean retinal sensitivity with vision-related quality of life in patients with idiopathic macular hole / 中华实验眼科杂志

ABSTRACT

Objective To evaluate the relationship of retinal sensitivity (MS) with vision-related quality of life in patients with idiopathic macular hole (IMH).Methods A prospective cohort study was performed in this study.Thirty-one monocular IMH patients were enrolled in Beijing Tongren Hospital from May to September of 2017.Vision-related quality of life (VR-QoL) was analyzed in 31 patients with National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) (Chinese version),and MS in the affected eye and the fellow eye in these patients was detected by Microperimeter-3.MS and best corrected visual acuity (BCVA) between the affected eye and the fellow eye were compared.The correlations among BCVA,age,MS,minimum macular hole diameter,composite scores and subscales score were evatuateds.This study protocol was approved by Ethic Committee of Beijing Tongren Hospital.This study complied with Declaration of Helsinki.Results There were significant correlations between composite scores and MS in the affected eye and the fellow eye (affected eyeρ=0.484,P=0.006;fellow eyeρ=0.387,P =0.031).Significante correlations were shown in near activities (affected eyeρ =-0.353,P =0.048;fellow eyeρ =0.352,P =0.048) and distance activities (affected eyeρ =0.496,P =0.004;fellow eyeρ =0.415,P =0.015).No obvious correlations were shown between VR-QoL and BCVA or minimum hole diameter.The correlation between composite scores and the MS in the affected eye was the most strong.Conclusions MS can reflect the retinal function in patients of IMH more widely.The correlations VR-QoL and MS is correlated in the affected eye and fellow eye in patients of monocular IMH,however,patient's VR-QoL dependes more on the affected eye.IMH can violate the patient's near and distance activities.