Clinical value of dynamic enhancement combined with diffusion-weighted MRI in the diagnosis of benign and malignant breast lesions / 中国基层医药

ABSTRACT

Objective To explore the clinical effect of dynamic enhancement combined with diffusion -weighted magnetic resonance imaging( MRI) in the diagnosis of benign and malignant breast lesions. Methods From January 2017 to January 2018,100 patients with breast lesions in Zhoushan Hospital were selected in the study. The patients received MR-DWI and DCE-MRI inspection,and the results were compared with the pathological verification results. Results The ADC value of benign breast lesions was (1. 65 ± 0. 24) × 10 -3 mm2/s. The ADC value of malignant breast lesions was (1. 17 ± 0. 17) × 10 -3 mm2/s,and there was statistically significant difference in ADC value between patients with benign and malignant breast lesions(t=5. 021,P<0. 05). The number of type Ⅰ,typeⅡ and type Ⅲ curve cases of 88 patients with benign lesions was 62 cases(70. 45％),18 cases(20. 45％) and 8 cases(9. 09％),respectively. The number of patients with type Ⅰ,type Ⅱ and type Ⅲ curve of malignant lesion was 3 cases(15. 00％),5 cases(25. 00％) and 12 cases(60. 00％),respectively. For dynamic enhancement type Ⅰand type Ⅲ curve in breast benign and malignant lesions,the difference was statistically significant(χ2 =8. 254,P<0. 05). The area under the curve of the joint diagnosis compared with the simple use of ADC and DEC-MRI,the difference was statistically significant(χ2 =6. 032,P<0. 05). The ADC compared with DEC-the area under the curve of MRI in the diagnosis had no obvious difference(χ2 =5. 221,P>5. 221). Conclusion The integrated use of DWI and DCE-MRI can lay the solid data for the diagnosis of breast malignant tumor,and effectively strengthen the diagnostic sensitivity and specificity,and make clinical intervention and clinical treatment easily.