The relationship between follice-stimulating hormone and its receptor in male reproduction / 中国医师杂志

ABSTRACT

Follicle stimulating hormone (FSH) is the key endocrine hormone regulating the gonadal function of both sexes.FSH stimulates male testicular Sertoli differentiation,promotes testicular development,and mitosis of spermatogonia.FSH maintains adult Sertoli cell metabolism and plays an important role in spermatogenesis,germ cell survival and male fertility.FSH and follicle-stimulating hormone receptor (FSHR) gene mutation or gene polymorphism may affect the role of FSH on target organs.This article reviews the relationship between FSH and FSHR and male reproductive relationship.