A Case of Anti-Glomerular Basement Membrane Antibody Associated Crescentic Glomerulonephritis with Positive Antineutrophilic Cytoplasmic Antibody / 대한신장학회잡지
Korean Journal of Nephrology
;
: 656-660, 1999.
Article
in Korean
| WPRIM
| ID: wpr-73441
ABSTRACT
A 63-year-old woman presented to the hospital with gross hematuria and acute renal failure. Kidney function deteriorated rapidly and progressively. A renal biopsy revealed segmental or circumferential crescents associated with linear deposits of immunoglobulin G, typical of anti-glomerular basement membrane disease. Both c-ANCA and anti-GBM antibody were detected in serum. She was treated with hemodialysis, plasmapheresis, high dose steroid and cyclophosphamide. However, she died 7 weeks after treatment because of pneumonia, without recovery of renal function. Serologic positivity of both ANCA and anti-GBM antibody are becoming more frequently recognized in rapidly progressive glomerulonephritis. The influence of c-ANCA on the clinical course of anti-GBM glomerulonephritis remains to be determined.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Basement Membrane
/
Biopsy
/
Immunoglobulin G
/
Renal Dialysis
/
Plasmapheresis
/
Antibodies, Antineutrophil Cytoplasmic
/
Anti-Glomerular Basement Membrane Disease
/
Cyclophosphamide
/
Cytoplasm
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
1999
Type:
Article
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