The role of one-hour post-load hyperglycemia in prediction and prevention of type 2 diabetes / 中华内分泌代谢杂志

ABSTRACT

One-hour post-load glucose concentration (1hPG) ≥155 mg/dl (8.6 mmol/L) in individuals with normal glucose tolerance (NGT) was correlated with increased risk for type 2 diabetes mellitus. This paper is the Chinese translation " One-hour post-load hyperglycemia implications for prediction and prevention of type 2 diabetes" , published on " The Journal of Clinical Endocrinology & Metabolism" [ Fiorentino TV, Marini MA, Succurro E, et al. J Clin Endocrinol Metab, 2018,103(9)3131-3143] after obtaining the copyright of the original journal. In this review, the authors analyzed the role of 1hPG measurement in prediction of type 2 diabetes and cardiovascular disease. They used MEDLINE and included all English studies published up to February 2018 in peer-reviewed journals that examined the relationship between 1hPG and diabetes, cardio-metabolic alterations, organ damage, and cardiovascular disease. The results showed that although 1hPG was not adopted by American Diabetes Association for identifying high-risk individuals, the available evidence indicated that, among subjects with NGT, a value of 1hPG≥155 mg/dl is helpful to identify those at increased risk of type 2 diabetes and cardiovascular disease.