Therapeutic effect and safety of conbercept intravitreal injection combined with selective laser photocoagulation on CRVO / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To investigate the efficacy and safety of conbercept intravitreal injection combined with selective laser photocoagulation for central retinal vein occlusion(CRVO).<p>METHODS: A retrospective study was performed on 66 patients with CRVO in our department of ophthalmology. Among them, 30 patients received only conbercept's intravitreal injection and served as a control group. On this basis, another 36 patients were combined with selective laser photocoagulation and as an observation group. The differences of central macular thickness(CMT), BCVA(LogMAR)and complication rate after treatment were compared between the two groups.<p>RESULTS:The CMT and BCVA of the two groups were significantly improved after treatment(<i>P</i><0.05). The CMT and BCVA of the observation group were significantly better than the control group at 6th month after treatment(<i>P</i><0.05). The number of intravitreal injections in the observation group was significantly lower than that in the control group(<i>P</i><0.05). There was no significant difference in the complications(<i>P</i>>0.05).<p>CONCLUSION: The combination therapy has a more significant effect on CRVO and is safe.