Effects of estrogen on neuron structure and expression of estrogen receptor in hypotha-lamus / 第三军医大学学报
Journal of Third Military Medical University
; (24): 318-320, 2001.
Article
in Zh
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| ID: wpr-735490
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ABSTRACT
Objective To explore the changes of ER-IR and the ultra structure in the medial preoptic area, arcuate nuclei of early-aged mice treated with estrogen. Methods Immunohistochemistry assay and electron microscopy were used in this study. Results ER-IR in the medical preoptic area and arcuate nuclei were greatly reduced after estrogen was given. The cell nuclei of neurons in these areas migrated towards the side, the nuclear membrane became folded, synapse became richer, and the number of synapse vesicle increased. Conclusion Estrogen can affect the neuron structure and function through the change of estrogen receptor expression in the medial preoptic area and arcuate nuclei of the hypothalamus cardiovascular center.
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Language:
Zh
Journal:
Journal of Third Military Medical University
Year:
2001
Type:
Article