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Incidence and risk factors of HIV infection among sero-negative spouses of HIV patients in Dehong prefecture of Yunnan province / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 996-1000, 2010.
Article in Chinese | WPRIM | ID: wpr-735884
ABSTRACT
Objective To study the HIV incidence and risk factors among sero-negative spouses of HIV patients in Dehong prefecture of Yunnan province. Methods A cohort of sero-negative spouses of the HIV patients had been developed and followed up since November, 2005.HIV new infections and related behaviors had been investigated every six months. Results By the end of June, 2008, 790 sero-negative spouses of HIV patients had been recruited, of whom 702 were followed-up for at least one time. During the total 1202.35 person-years, 31 new HIV infections were identified, with an overall incidence of 2.58/100 preson-years. The HIV incidence rates were 2.22/100person-years in 2006, 2.95/100 person-years in 2007 and 2.74/100 person-years in 2008. Data from the Cox proportional hazard regression model indicated that those who resided in Yingjiang county [hazard ratio (HR) =4.37, 95% CI 1.48-12.90, P=0.008] , ever using drugs (HR=3.49, 95% CI1.09-11.18, P=0.035) , or having an HIV-infected spouse who never exposed to antiretroviraltreatment (HR=3.60, 95% CI 1.41-9.16, P=0.007) were at higher risk for HIV infection.Conclusion Sero-negative spouses of HIV patients in Dehong prefecture of Yunnan province had a relatively high incidence of HIV new infection during 2006-2008. More efforts should put on those people living in these areas, having a history of drug use or having an HIV-infected spouse who had never been exposed to antiretroviral treatment.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Incidence study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Epidemiology Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Incidence study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Epidemiology Year: 2010 Type: Article