Effect of air pollution on pregnancy outcome of women at reproductive age in Xi'an, 2010-2013 / 中华流行病学杂志

ABSTRACT

Objective To compare the differences in the incidence of adverse pregnancy outcome in different area,and confirm if the incidence of adverse pregnancy outcomes is closely associated with air pollution.Methods A cross-sectional study was conducted in the central urban area and the rural-urban area of Xi'an through a questionnaire survey conducted among the local reproductive women selected through multistage stratified random sampling during 2010-2013,all the reproductive women surveyed were in pregnancy or had definite pregnancy outcomes.Results The annual average of SO2 concentration in the central urban area was 38-54 μg/m3,higher than that in the rural-urban area (29-43 μg/m3).The annual average NO2 concentration in the central urban area was 29-87 μg/m3,higher than that in the rural-urban area (22-42 μg/m3).The incidence of birth defects was higher in the central urban area than in the rural-urban area (2.1％ vs.1.0％),the difference was significant (P＜0.05).After adjusting for confounding factors,logistic regression analysis showed the incidence of birth defects in the central urban area was still significantly higher than that in the rural-urban area,the difference was significant (P＜0.05).Conclusion The incidence of adverse pregnancy was closely associated with the level of air pollution.