Detecting telomerase activity of gastrointestinal tract cancerous cell lines by TRAP-ELISA / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 378-380, 2001.
Article
in Zh
| WPRIM
| ID: wpr-736857
Responsible library:
WPRO
ABSTRACT
Objective: To select the telomerase positive cancer cell lines of gastrointestinal tract and to provide a convinced methodology for future telomerase study. Methods: Fifteen cancer cell lines (carcinoma of stomach 4, of liver 6, of pancreas 2, of colon 3) were cultured and telomerase activity were detected by TRAP-ELISA. The normal hepatic cells were taken as control. Results: Thirteen cell lines were telomerase positive in the 15 lines(86.7%). Conclusion: Most of gastrointestinal tract cancer lines express telomerase, indicating the detection of telomerase activity has clinical potential.
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Language:
Zh
Journal:
Academic Journal of Second Military Medical University
Year:
2001
Type:
Article