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Gender differences in stressful life events and depression in Chinese adults aged 30-79 years / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 1449-1453, 2017.
Article in Chinese | WPRIM | ID: wpr-737851
ABSTRACT
Objective To investigate gender specific differences in the association between stressful life events (SLEs) and depression in Chinese adults aged 30-79 years. Methods In the baseline survey during 2004-2008, the China Kadoorie Biobank (CKB) recruited 512891 men and women aged 30-79 years from 10 areas of China. Detailed information on SLEs, including demographic and socio-economic status, smoking, alcohol drinking and history of chronic disease, as well as depression symptoms and major depressive episodes (MDEs) in preceding 12 months, was collected by using standardized questionnaire. Multinomial logistic regression model was employed to estimate the relative risk ratio (RRR) and 95%CI of SLEs (3 categories, 10 items) on depression and the dose-response relationship between the number of SLEs experienced and depression. The interactions between gender and SLEs on depression were examined with likelihood ratio test. Results Among the 512891 participants, 35085 (6.8%) reported family-related events, 5972 (1.2%) reported finance-related events, and 4453 (0.9%) reported other stressful life events. Females had a higher occurrence of family-related events, while males had a higher occurrence of finance-related and other events (all P-value <0.001). After adjusted for potential confounders, SLEs were significantly associated with MDEs (RRR=11.99, 95%CI 10.49-13.71 for males; RRR=14.15, 95%CI 12.97-15.43 for females), and with depressive symptoms (RRR=7.43, 95%CI6.94-7.95 for males;RRR=8.30, 95%CI 7.91-8.72 for females). And the associations were stronger in females than in males (P for interaction=0.049). In the three categories of SLEs, family-related events showed stronger association in female (P for interaction<0.001), while no gender specific differences were observed for the other two categories (all P-value>0.05). Furthermore, the effect of the number of SLEs experienced increased in a dose-response manner on depressive symptoms and MDEs for both genders, but no gender specific differences were found. Conclusions The gender modifies the association between stressful life events and depression in Chinese adults, and women experienced family-related events have a greater risk of depression. The more the stressful events experienced, the more likely to have depression.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Epidemiology Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Epidemiology Year: 2017 Type: Article