Primary Cutaneous Carcinosarcoma Composed of Squamous Cell Carcinoma and Epithelioid Sarcoma / 대한피부과학회지
Korean Journal of Dermatology
;
: 145-148, 2016.
Article
in Korean
| WPRIM
| ID: wpr-73820
ABSTRACT
Cutaneous carcinosarcoma is a biphasic, rare tumor composed of malignant epithelial and mesenchymal components. The most common carcinoma component is a squamous cell carcinoma and the most common sarcoma component is an osteosarcoma. A 74-year-old female patient presented to our hospital with a 3.5x3.5 cm-sized exophytic, eroded tumor surrounded by an erythematous plaque on her right flank that had been present for 10 years. On the incisional biopsy specimen, the tumor was composed of atypical malignant squamous cells and epithelioid cells. Furthermore, immunohistochemistry revealed that the tumor cells were positive to cytokeratin AE1/AE3, cytokeratin 5/6, epithelial membrane antigen, p63, and vimentin but were negative to HMB45, S-100, CD31, CD34, factor VIII, smooth muscle actin, and desmin. Finally, based on these histopathological and immunohistochemical findings, we diagnosed this tumor as cutaneous carcinosarcoma consisting of squamous cell carcinoma and epithelioid sarcoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sarcoma
/
Vimentin
/
Biopsy
/
Factor VIII
/
Immunohistochemistry
/
Carcinoma, Squamous Cell
/
Carcinosarcoma
/
Osteosarcoma
/
Epithelioid Cells
/
Actins
Limits:
Aged
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2016
Type:
Article
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