Effect of vitamin C ingestion on the vascular endothelial function exposed to transient passive smoking / 体力科学
Japanese Journal of Physical Fitness and Sports Medicine
;
: 153-157, 2019.
Article
in Japanese
| WPRIM
| ID: wpr-738398
ABSTRACT
As well as active smoking, passive smoking is associated with a high risk of developing cardiovascular disease. The antioxidant vitamin C may inhibit the unfavorable effects of passive smoking. In this study, we investigated the effects of vitamin C ingestion on changes in the flow-mediated dilatation (FMD) at the brachial artery in patients exposed to transient passive smoking. The study participants included seven healthy adult males who were examined by high-resolution ultrasonography of the brachial artery before and after 15-minute of passive smoking. FMD was used to examine the endothelial function. Randomized crossover controlled trial, measurements were performed on two different days 120-minute after the oral administration of 1000mg of ascorbic acid (VC trial) or a placebo (P trial). Although the FMD values decreased after passive smoking in both trials, the FMD values of the VC trial were higher than those of the P trial, with significant differences between the trials observed immediately and 30-minute after passive smoking. The results of this study suggested that the ingestion of vitamin C may suppress the decrease in the vascular endothelial function caused by transient passive smoking.
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Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Japanese
Journal:
Japanese Journal of Physical Fitness and Sports Medicine
Year:
2019
Type:
Article
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