Poorly Differentiated Neuroendocrine Carcinoma of the Eyelid
Journal of the Korean Ophthalmological Society
;
: 861-866, 2018.
Article
in Korean
| WPRIM
| ID: wpr-738580
ABSTRACT
PURPOSE:
To report a case of poorly differentiated neuroendocrine carcinoma of the eyelid. CASESUMMARY:
A 70-year-old male presented with a 5-month history of a right upper eyelid mass. The mass appeared as 1.2 × 1.2 cm on the right upper eyelid. A mass excision was performed under frozen section control. The tumor was completely excised with a safety margin clearance and an upper eyelid reconstruction was performed. Histopathological examination revealed a tumor composed of small atypical cells which showed a high nuclear/cytoplasm ratio, nuclear molding, and increased mitotic activity. Immunohistochemical examination revealed positive reactivity for Ki-67, synaptophysin, CD56, and negative reactivity for chromogranin, cytokeratin 20, and thyroid transcription factor-1.CONCLUSIONS:
Primary neuroendocrine carcinoma of the eyelid is extremely rare, but the tumor has high malignancy and readily metastasizes. Poorly differentiated neuroendocrine carcinoma should be considered in the differential diagnosis of a rapidly growing eyelid mass.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Carcinoma, Merkel Cell
/
Synaptophysin
/
Carcinoma, Small Cell
/
Carcinoma, Neuroendocrine
/
Diagnosis, Differential
/
Keratin-20
/
Eyelids
/
Frozen Sections
/
Fungi
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2018
Type:
Article
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