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Bilateral Rhegmatogenous Retinal Detachments after Systemic Pazopanib Treatment
Journal of the Korean Ophthalmological Society ; : 491-495, 2019.
Article in Korean | WPRIM | ID: wpr-738625
ABSTRACT

PURPOSE:

A case of bilateral rhegmatogenous retinal detachment is reported after pazopanib treatment of a patient with breast angiosarcoma. CASE

SUMMARY:

A 53-year-old female presented with bleeding in a right breast mass prior to an emergency room visit. She was diagnosed with metastatic breast angiosarcoma after a breast mass biopsy. She was treated with paclitaxel and radiation therapy. Systemic pazopanib treatment was added to treat lung metastasis. After 3 weeks, she felt sudden floaters in her right eye. In her fundus examination, there was vitreous hemorrhage, but no retinal detachment was noted. Five weeks later, she visited the clinic for a bilateral temporal visual field defect. A fundus examination showed bilateral retinal detachments with superonasal retinal tears. Both the patient and her family did not want surgery for her systemic condition because of her terminal cancer.

CONCLUSIONS:

Retinal detachment has been reported as a rare complication after systemic pazopanib treatment, but there has been no previous report in the Republic of Korea, therefore this is the first case of bilateral retinal detachments after systemic pazopanib treatment.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Retinal Perforations / Retinaldehyde / Biopsy / Vitreous Hemorrhage / Breast / Retinal Detachment / Visual Fields / Paclitaxel / Emergency Service, Hospital / Republic of Korea Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Retinal Perforations / Retinaldehyde / Biopsy / Vitreous Hemorrhage / Breast / Retinal Detachment / Visual Fields / Paclitaxel / Emergency Service, Hospital / Republic of Korea Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2019 Type: Article