Methimazole-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in the Peripheral Nerves
International Journal of Thyroidology
;
: 176-181, 2018.
Article
in English
| WPRIM
| ID: wpr-738939
ABSTRACT
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis has been reported in Graves' disease patients treated with antithyroid drugs (ATDs), especially propylthiouracil. ATD-induced ANCA-associated vasculitis usually involved the kidneys followed by the respiratory organs and skin. The treatment of ANCA-associated vasculitis induced by ATDs is to stop ATD therapy immediately, which often leads to an overall good prognosis. We report a case of ANCA-associated vasculitis in the peripheral nerves of the lower extremities in a 66-year-old woman who was treated with methimazole (MMI) for Graves' disease. To our knowledge, this is the third case of peripheral nervous system (PNS) involvement of ATD-induced vasculitis and the first case of PNS vasculitis associated with MMI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peripheral Nerves
/
Prognosis
/
Propylthiouracil
/
Skin
/
Antithyroid Agents
/
Vasculitis
/
Graves Disease
/
Peripheral Nervous System
/
Antibodies, Antineutrophil Cytoplasmic
/
Lower Extremity
Type of study:
Prognostic study
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
International Journal of Thyroidology
Year:
2018
Type:
Article
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