Critical effects of long non-coding RNA on fibrosis diseases
Experimental & Molecular Medicine
;
: e428-2018.
Article
in English
| WPRIM
| ID: wpr-739497
ABSTRACT
The expression or dysfunction of long non-coding RNAs (lncRNAs) is closely related to various hereditary diseases, autoimmune diseases, metabolic diseases and tumors. LncRNAs were also recently recognized as functional regulators of fibrosis, which is a secondary process in many of these diseases and a primary pathology in fibrosis diseases. We review the latest findings on lncRNAs in fibrosis diseases of the liver, myocardium, kidney, lung and peritoneum. We also discuss the potential of disease-related lncRNAs as therapeutic targets for the clinical treatment of human fibrosis diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Peritoneum
/
Autoimmune Diseases
/
Fibrosis
/
RNA, Long Noncoding
/
Genetic Diseases, Inborn
/
Kidney
/
Liver
/
Lung
/
Metabolic Diseases
Limits:
Humans
Language:
English
Journal:
Experimental & Molecular Medicine
Year:
2018
Type:
Article
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