Association between Changes in Anthropometric Indices and in Fasting Insulin Levels among Healthy Korean Adolescents: The JS High School Study
Diabetes & Metabolism Journal
;
: 183-191, 2019.
Article
in English
| WPRIM
| ID: wpr-739803
ABSTRACT
BACKGROUND:
This study investigated the association between changes in anthropometric indices and fasting insulin levels among healthy adolescents and whether the association differed by baseline obesity status.METHODS:
This analysis was based on data collected for the JS High School study; 884 healthy adolescents aged 15 to 16 years followed up for 24 to 30 months were included. Changes in anthropometric indices and fasting insulin levels were computed as the difference between baseline and follow-up values. Multivariate linear regression models were used to determine the association between changes in anthropometric indices and fasting insulin levels. Based on body mass index (BMI)-for-age and waist circumference (WC)-for-age percentiles, participants were classified as normal weight (<85th percentile), overweight (85th percentile to <95th percentile), or obese (≥95th percentile).RESULTS:
Changes in BMI, WC, waist-hip ratio, and waist-height ratio were significantly associated with changes in fasting insulin levels in both sexes (P<0.05). In analyses stratified by baseline obesity status, the association between change in BMI and change in fasting insulin was significantly stronger in overweight (males standardized β=1.136; females standardized β=1.262) and obese (males standardized β=1.817; females standardized β=2.290) participants than in those with normal weight (males standardized β=0.957; females standardized β=0.976) at baseline. Results were similar for changes in WC.CONCLUSION:
Changes in anthropometric indices were positively associated with fasting insulin level increases. Moreover, those who were overweight or obese at baseline had a higher absolute increase in fasting insulin levels per one standard deviation unit increase in anthropometric indices than adolescents with normal weight.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Body Mass Index
/
Linear Models
/
Follow-Up Studies
/
Fasting
/
Waist-Hip Ratio
/
Overweight
/
Waist Circumference
/
Waist-Height Ratio
/
Insulin
/
Obesity
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Female
/
Humans
Language:
English
Journal:
Diabetes & Metabolism Journal
Year:
2019
Type:
Article
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