Secondary Adrenal Insufficiency Associated with Megestrol Acetate in a Patient with Lung Cancer / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 47-51, 2009.
Article
in Korean
| WPRIM
| ID: wpr-73994
ABSTRACT
Loss of appetite is an important factor in the quality of life for advanced cancer patients. Megestrol acetate is used to stimulate appetite, but it can cause suppression of the pituitary adrenal axis due to the affinity of the glucocorticoid receptor. Adrenal insufficiency is a life threatening disorder if left, untreated, but the initial clinical symptoms of the patients are vague. Awareness of the glucocorticoid-like activity of megestrol acetate and its side effects are important for the diagnosis of adrenal insufficiency. We present a case of secondary adrenal insufficiency associated with megestrol acetate in a patient with lung cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Appetite
/
Quality of Life
/
Axis, Cervical Vertebra
/
Receptors, Glucocorticoid
/
Adrenal Insufficiency
/
Megestrol Acetate
/
Lung
/
Lung Neoplasms
/
Megestrol
Limits:
Humans
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS