Complications caused by nitrous oxide in dental sedation
Journal of Dental Anesthesia and Pain Medicine
;
: 71-78, 2018.
Article
in English
| WPRIM
| ID: wpr-739959
ABSTRACT
The first clinical application of nitrous oxide (N₂O) was in 1844, by an American dentist named Horace Wells who used it to control pain during tooth extraction. Since then, N₂O has shared a 170-year history with modern dental anesthesia. N₂O, an odorless and colorless gas, is very appealing as a sedative owing to its anxiolytic, analgesic, and amnestic properties, rapid onset and recovery, and, in particular, needle-free application. Numerous studies have reported that N₂O can be used safely and effectively as a procedural sedation and analgesia (PSA) agent. However, N₂O can lead to the irreversible inactivation of vitamin B12, which is essential for humans; although rare, this can be fatal in some patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tooth Extraction
/
Vitamin B 12
/
Conscious Sedation
/
Dentists
/
Analgesia
/
Anesthesia, Dental
/
Nitrous Oxide
Limits:
Humans
Language:
English
Journal:
Journal of Dental Anesthesia and Pain Medicine
Year:
2018
Type:
Article
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