Comparative randomized study of propofol target-controlled infusion versus sevoflurane anesthesia for third molar extraction
Journal of Dental Anesthesia and Pain Medicine
;
: 169-175, 2018.
Article
in English
| WPRIM
| ID: wpr-739964
ABSTRACT
BACKGROUND:
The objective of this study was to compare hemodynamic and recovery characteristics of total intravenous anesthesia using propofol target-controlled infusion (TCI) versus sevoflurane for extraction of four third molar teeth.METHODS:
One hundred patients undergoing extraction of four third molar teeth under general anesthesia were randomized to one of two groups. Group 1 received propofol TCI-oxygen for induction and propofol TCI-oxygen-air for maintenance. Group II received a propofol bolus of 2 mg/kg for induction and sevoflurane-oxygen-air for maintenance. Heart rate, mean arterial pressure (MAP), operating time, time to emergence, nausea and vomiting, and sedation and pain scores were measured in each group.RESULTS:
Demographic data, including age, gender, weight, and height, were not significantly different between the two groups. The MAP was significantly higher after intubation (P = 0.007) and injection of anesthesia (P = 0.004) in the propofol group than in the sevoflurane group, with significant reflex bradycardia (P = 0.028). The mean time to emergence from anesthesia using propofol was 25 s shorter than that of sevoflurane (P = 0.02). Postoperatively, the propofol group was less sedated than the sevoflurane group at 30 min (0.02 versus 0.12), but this difference was not significant (P = 0.065).CONCLUSION:
Both propofol TCI and sevoflurane are good alternatives for induction and maintenance of anesthesia for short day-case surgery. However, propofol TCI does not blunt the hemodynamic response to sudden, severe stimuli as strongly as sevoflurane, and this limitation may be a cause for concern in patients with cardiac comorbidities.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reflex
/
Tooth
/
Vomiting
/
Bradycardia
/
Comorbidity
/
Propofol
/
Arterial Pressure
/
Heart Rate
/
Hemodynamics
/
Intubation
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
English
Journal:
Journal of Dental Anesthesia and Pain Medicine
Year:
2018
Type:
Article
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