Antimicrobial Effect of Ethanol Extract of Garcinia mangostana L. against Enterococcus faecalis Isolated from Human Oral Cavity
International Journal of Oral Biology
;
: 129-132, 2018.
Article
in Korean
| WPRIM
| ID: wpr-740077
ABSTRACT
Enterococcus faecalis is a major causative agent of endodontic treatment failure. The purpose of this study was to investigate bactericidal effects of ethanol extract of Garcinia mangostana L. (mangosteen extract) on five strains of E. faecalis that were isolated from human oral cavities. The bactericidal effects of mangosteen extract were assessed by measurement of minimum bactericidal concentration (MBC) value. The cytotoxicity of mangosteen extract on immortalized human gingival fibroblasts, hTERT-hNOF, was determined based on cell counting method. The data revealed the MBC value of mangosteen extract against the E. faecalis strains was 4 µg/ml. Additionally, the cell viability of mangosteen extract on hTERT-hNOF was 83.7–89.1% at the 1 to 16 µg/ml. These findings indicated that mangosteen extract could be used as a root canal cleaner during management of endodontic treatment failure caused by E. faecalis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cell Count
/
Cell Survival
/
Enterococcus
/
Enterococcus faecalis
/
Treatment Failure
/
Garcinia
/
Garcinia mangostana
/
Dental Pulp Cavity
/
Ethanol
/
Fibroblasts
Limits:
Humans
Language:
Korean
Journal:
International Journal of Oral Biology
Year:
2018
Type:
Article
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