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Comparison of Contrast-Enhanced T2 FLAIR and 3D T1 Black-Blood Fast Spin-Echo for Detection of Leptomeningeal Metastases
Investigative Magnetic Resonance Imaging ; : 86-93, 2018.
Article in English | WPRIM | ID: wpr-740135
ABSTRACT

PURPOSE:

Imaging plays a significant role in diagnosing leptomeningeal metastases. However, the most appropriate sequence for the detection of leptomeningeal metastases has yet to be determined. This study compares the efficacies of contrast-enhanced T2 fluid attenuated inversion recovery (FLAIR) and contrast-enhanced 3D T1 black-blood fast spin echo (FSE) imaging for the detection of leptomeningeal metastases. MATERIALS AND

METHODS:

Tube phantoms containing varying concentrations of gadobutrol solution were scanned using T2 FLAIR and 3D T1 black-blood FSE. Additionally, 30 patients with leptomeningeal metastases were retrospectively evaluated to compare conspicuous lesions and the extent of leptomeningeal metastases detected by T2 FLAIR and 3D T1 black-blood FSE.

RESULTS:

The signal intensities of low-concentration gadobutrol solutions (< 0.5 mmol/L) on T2 FLAIR images were higher than in 3D T1 black-blood FSE. The T2 FLAIR sequences exhibited significantly greater visual conspicuity scores than the 3D T1 black-blood sequence in leptomeningeal metastases of the pial membrane of cistern (P = 0.014). T2 FLAIR images exhibited a greater or equal extent (96.7%) of leptomeningeal metastases than 3D T1 black-blood FSE images.

CONCLUSION:

Because of its high sensitivity even at low gadolinium concentrations, contrast-enhanced T2 FLAIR images delineated leptomeningeal metastases in a wider territory than 3D T1 black-blood FSE.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Retrospective Studies / Gadolinium / Membranes / Neoplasm Metastasis Type of study: Diagnostic study / Observational study Limits: Humans Language: English Journal: Investigative Magnetic Resonance Imaging Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Retrospective Studies / Gadolinium / Membranes / Neoplasm Metastasis Type of study: Diagnostic study / Observational study Limits: Humans Language: English Journal: Investigative Magnetic Resonance Imaging Year: 2018 Type: Article