Clinical Safety and Efficacy of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Sensorineural Hearing Loss Patients
Journal of Audiology & Otology
;
: 105-109, 2018.
Article
in English
| WPRIM
| ID: wpr-740320
ABSTRACT
Stem cell transplantation represents a promising therapy for several degenerating and necrotic diseases. In several animal studies, we could find hearing restoration after inoculation of the mesenchymal stem cells' as well as mesenchymal stem cells' differentiation of hair cells and spiral ganglion. But until now, no clinical study has been reported directly for the human being. In this pilot studies, we applied mesenchymal stem cells to human beings trans-venously. Although we verified the safety of the autologous bone marrow stem cell transplantation in sensorineural hearing loss patients but we could not achieve significant improvement in hearing.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bone Marrow
/
Pilot Projects
/
Spiral Ganglion
/
Stem Cell Transplantation
/
Mesenchymal Stem Cell Transplantation
/
Electric Stimulation
/
Mesenchymal Stem Cells
/
Clinical Study
/
Hair
/
Hearing
Limits:
Animals
/
Humans
Language:
English
Journal:
Journal of Audiology & Otology
Year:
2018
Type:
Article
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