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Inflammatory Myofibroblastic Tumor Showing Durable Remission after Anthracycline-Containing Cytotoxic Chemotherapy: Report of a Case / 대한내과학회지
Korean Journal of Medicine ; : 749-753, 2012.
Article in Korean | WPRIM | ID: wpr-741103
ABSTRACT
An inflammatory myofibroblastic tumor (IMT) is a rare disease entity, and the clinical characteristics range from indolent to aggressive forms. No established management for patients with unresectable or aggressive IMT is available. We report on a 62-year-old patient with aggressive IMT who achieved a durable partial response lasting 12 months after anthracycline-containing cytotoxic chemotherapy without corticosteroids. The patient was admitted for an evaluation of progressive weight loss and lower abdominal pain lasting for 2 weeks. Abdominopelvic computed tomography revealed a 10 cm sized heterogeneous mass in the mesentery that encased the superior mesenteric artery and a liver metastasis. The diagnosis of IMT was confirmed by percutaneous core needle biopsy of the mesenteric mass. Systemic chemotherapy was performed after confirming disease progression during a 1 month observation period. A partial response was obtained after two cycles of chemotherapy. Anthracycline-containing cytotoxic chemotherapy could be a treatment option for patients with aggressive IMT.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Piperidones / Weight Loss / Abdominal Pain / Mesenteric Artery, Superior / Adrenal Cortex Hormones / Disease Progression / Rare Diseases / Benzeneacetamides / Myofibroblasts / Biopsy, Large-Core Needle Limits: Humans Language: Korean Journal: Korean Journal of Medicine Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Piperidones / Weight Loss / Abdominal Pain / Mesenteric Artery, Superior / Adrenal Cortex Hormones / Disease Progression / Rare Diseases / Benzeneacetamides / Myofibroblasts / Biopsy, Large-Core Needle Limits: Humans Language: Korean Journal: Korean Journal of Medicine Year: 2012 Type: Article