Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review
Journal of Pathology and Translational Medicine
;
: 344-348, 2018.
Article
in English
| WPRIM
| ID: wpr-741186
ABSTRACT
Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are so named because they usually occur in children and adolescents. A 71-year-old woman with right upper quadrant abdominal pain visited our hospital. Pelvic computed tomography showed a large multilocular cystic mass, suspected to be of ovarian origin. We performed a total abdominal hysterectomy (total abdominal hysterectomy was performed) with bilateral salpingo-oophorectomy. A 13-cm multilocular cystic mass with serous fluid was observed in her right ovary. Upon microscopic examination, the solid component of the mass showed both Sertoli-Leydig cell and juvenile granulosa cell differentiation, which we diagnosed as gynandroblastoma. Gynandroblastoma with a juvenile granulosa cell tumor component is extremely rare and, until now, only six cases have been reported in the English literature. We report the first gynandroblastoma with a juvenile granulosa cell tumor component diagnosed in an elderly patient, along with a literature review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovary
/
Abdominal Pain
/
Sex Cord-Gonadal Stromal Tumors
/
Postmenopause
/
Granulosa Cell Tumor
/
Granulosa Cells
/
Hysterectomy
Limits:
Adolescent
/
Aged
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Pathology and Translational Medicine
Year:
2018
Type:
Article
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