Cytopathologic Features of Secretory Carcinoma of Salivary Gland: Report of Two Cases
Journal of Pathology and Translational Medicine
;
: 70-74, 2019.
Article
in English
| WPRIM
| ID: wpr-741205
ABSTRACT
Secretory carcinoma of the salivary gland (SC) is a newly introduced rare salivary gland tumor that shares histological, immunohistochemical, and genetic characteristics with secretory carcinoma of the breast. Here, we report the cytologic features of two cases of SC confirmed by surgical resection. In these two cases, SC was incidentally detected in a 64-year-old female and a 56-yearold male. Fine needle aspiration cytology revealed nests of tumor cells with a papillary or glandular structure floating in mucinous secretions. The tumor cells demonstrated uniform, round, smooth nuclear contours and distinct nucleoli. Multiple characteristic cytoplasmic vacuoles were revealed. Singly scattered tumor cells frequently showed variable sized cytoplasmic vacuoles. The cytopathologic diagnosis of SC should be considered when characteristic cytological findings are revealed. Further immunohistochemistry and gene analyses are helpful to diagnose SC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Salivary Glands
/
Vacuoles
/
Breast
/
Immunohistochemistry
/
Clothing
/
Cytoplasm
/
Biopsy, Fine-Needle
/
Diagnosis
/
Mammary Analogue Secretory Carcinoma
/
Mucins
Type of study:
Diagnostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Pathology and Translational Medicine
Year:
2019
Type:
Article
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