Drug eruption by antihistamine mistaken for chronic urticaria in a child / 소아과
Korean Journal of Pediatrics
;
: 75-78, 2019.
Article
in English
| WPRIM
| ID: wpr-741363
ABSTRACT
Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g., ucerax [hydroxyzine] or leptizine [levocetirizine]), for cholinergic rashes; he did not have pruritus. Skin prick, intradermal, and drug provocation tests were performed to determine the relationship between the antihistamines and eruptions. Levocetirizine induced wheals in the skin prick test and a rash in the oral drug provocation test. In contrast, ketotifen induced no reaction in the skin prick test but showed a positive reaction in the oral provocation test. Our case report highlights that children can experience the same types of adverse reactions as seen in adults, and cross-reactivity between various antihistamines can occur.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pruritus
/
Skin
/
Urticaria
/
Drug Eruptions
/
Exanthema
/
Histamine Antagonists
/
Anaphylaxis
/
Ketotifen
Limits:
Adult
/
Child
/
Child, preschool
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2019
Type:
Article
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