Evaluation of the efficacy of an attenuated live vaccine based on virulent porcine reproductive and respiratory syndrome virus 2 in young pigs / 대한수의학회지
Korean Journal of Veterinary Research
;
: 137-141, 2018.
Article
in English
| WPRIM
| ID: wpr-741511
ABSTRACT
The efficacy of the CA-2-MP120 vaccine, a cell culture-attenuated strain of virulent porcine reproductive and respiratory syndrome virus (PRRSV), was assessed in pigs. Despite the persistence of viremia in all vaccinated animals during the immunization period, the virus was not detected in vaccinated pigs following challenge. Furthermore, no pigs in the vaccinated group shed PRRSV nasally, orally or rectally throughout the experiment. Moreover, histopathological lung and lymph node lesions in the immunized group were much milder than those in the unimmunized and challenged group. These results indicated that CA-2-MP120 can provide effective protection against virulent wildtype PRRSV-2.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Swine
/
Viremia
/
Vaccines, Attenuated
/
Immunization
/
Vaccination
/
Treatment Outcome
/
Porcine respiratory and reproductive syndrome virus
/
Porcine Reproductive and Respiratory Syndrome
/
Lung
/
Lymph Nodes
Limits:
Animals
Language:
English
Journal:
Korean Journal of Veterinary Research
Year:
2018
Type:
Article
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