Predictors of Neurodevelopmental Outcomes in Newborns Undergoing Hypothermia Therapy
Neonatal Medicine
;
: 17-23, 2019.
Article
in Korean
| WPRIM
| ID: wpr-741668
ABSTRACT
PURPOSE:
This study aimed to identify the early predictors of neurodevelopmental outcomes in infants undergoing therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy.METHODS:
The medical records of 24 neonates who underwent hypothermia therapy for hypoxic ischemic encephalopathy at the neonatal intensive care unit of Yeouido St. Mary's Hospital of the Catholic University of Korea between August 2013 and May 2016 were reviewed. Patients were divided into two groups according to their neurological outcome at the age of 18 to 24 months a normal group (n=14), which included patients with normal neurological function, and an abnormal group (n=10), which included patients with neurological deficits. The clinical characteristics, clinical outcomes, and laboratory findings before and after hypothermia treatment were compared between the groups.RESULTS:
There were no significant differences in the demographic characteristics between the two groups. With regard to clinical outcomes, only brain magnetic resonance imaging (MRI) findings showed significant differences between the normal and abnormal groups (21.4% vs. 100.0%, P 0.05).CONCLUSION:
The presence of abnormal lesions on MRI was the most useful predictor of poor neurodevelopmental outcome in infants treated with therapeutic hypothermia after perinatal asphyxia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asphyxia
/
Brain
/
Magnetic Resonance Imaging
/
Intensive Care, Neonatal
/
Logistic Models
/
Medical Records
/
Risk Factors
/
Treatment Outcome
/
Hypoxia-Ischemia, Brain
/
Hypothermia
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Infant
/
Infant, Newborn
Country/Region as subject:
Asia
Language:
Korean
Journal:
Neonatal Medicine
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS