Association of Newly Developed Right Bundle Branch Block with Graft Rejection Following Heart Transplantation
Yonsei Medical Journal
;
: 423-428, 2019.
Article
in English
| WPRIM
| ID: wpr-742564
ABSTRACT
PURPOSE:
We aimed to examine associations between right bundle branch block (RBBB) following heart transplantation (HT) and graft rejection. MATERIALS ANDMETHODS:
We investigated 51 patients who underwent endomyocardial biopsies, electrocardiogram, right-side cardiac catheterization, and echocardiography at 1 month and 1 year after HT. We classified patients into four groups according to the development of RBBB, based on electrocardiogram at 1 month and 1 year 1) sustained RBBB, 2) disappeared RBBB, 3) newly developed RBBB, and 4) sustained non-RBBB. The RBBB was defined as an RSR' pattern in V1 with a QRS duration ≥100 ms on electrocardiogram.RESULTS:
The newly developed RBBB group (n=13, 25.5%) had a higher rate of new onset graft rejection (from grade 0 to grade ≥1R, 30.8% vs. 10.0% vs. 21.4%, p=0.042) at 1 year, compared with sustained RBBB (n=10, 19.6%) and sustained non-RBBB group (n=28, 54.9%). In contrast, the incidence of resolved graft rejection (from grade ≥1R to grade 0) was higher in the sustained RBBB group than the newly developed RBBB and sustained non-RBBB groups (70.0% vs. 7.7% vs. 25.0%, p=0.042). Left atrial volume index was significantly higher in the newly developed RBBB group than the sustained RBBB and sustained non-RBBB groups (60.6±25.9 mL/m2 vs. 36.0±11.0 mL/m2 vs. 38.4±18.1 mL/m2, p=0.003).CONCLUSION:
Close monitoring for new development of RBBB at 1 year after HT, which was associated with a higher incidence of new onset graft rejection, may be helpful to identify high risk patients for graft rejection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Bundle-Branch Block
/
Echocardiography
/
Cardiac Catheterization
/
Incidence
/
Heart Transplantation
/
Transplants
/
Electrocardiography
/
Cardiac Catheters
/
Graft Rejection
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2019
Type:
Article
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