Efficacy of FS-LASIK combined with rapid corneal collagen cross-linking for correction of high myopia / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To evaluate the efficacy of FS-LASIK combined with rapid corneal collagen cross-linking in treatment of high myopia.<p>METHODS: A prospective self-control study. Totally 42 patients(81 eyes)with high myopia treated by FS-LASIK combined with rapid corneal collagen cross-linking in our hospital from June to September 2017 were followed up for 6mo. The uncorrected visual acuity(UCVA), spherical equivalent(SE), corneal morphological parameters, corrected intraocular pressure and complications were observed.<p>RESULTS: At 6mo after operation, the UCVA(LogMAR)increased from 1.44±0.18 before operation to -0.03±0.04, the SE degree reduced from -8.01±1.23D to -0.06±0.54D, the steepest corneal curvature(Steep K)decreased from 44.23±0.80D to 37.39±1.17D at 6mo after operation, the flattest corneal curvature(Fleep K)decreased from 42.87±0.61D before operation to 36.84±0.99D after operation. And the thinnest point thickness of cornea decreased from 525.33±30.42μm to 402.12±28.04μm, the corrected intraocular pressure decreased from 17.77±2.16mmHg to 16.69±0.41mmHg. There were no significant changes in the posterior surface height of thinnest cornea and the endothelial cell density. No corneal infections, serious non-infectious inflammation and complications related to corneal flaps were found during follow-up.<p>CONCLUSION: FS-LASIK combined with rapid corneal collagen cross-linking is safe and effective in treatment of high myopia. The corneal morphology and refraction are relatively stable after surgery.