Serum specific IgE level analysis of patients with fungi induced allergic rhinitis in Beijing / 中国耳鼻咽喉头颈外科

ABSTRACT

OBJECTIVE To varify the difference of serum specific IgE levels in different ages and gender inpatients with Aspergillus fumigatus or Alternaria alternate induced allergic rhinitis. METHODS In this study, 85 patients with Aspergillus fumigatus or Alternaria alternate induced allergic rhinitis were included. sIgE tests was done by Immuno CAP 250TM System(Thermo Fisher Scientific, Uppsala, Sweden). RESULTS Mean level of aspergillus fumigatus sIgE was significantly lower than Alternaria alternate(P<0.05), single or dual fungi allergy show no impact on this difference. sIgE level showed positive correlation with age in Aspergillus fumigatus group(P <0.05), while negative in Alternaria alternate group(P <0.05). CONCLUSION Aspergillus fumigatus and Alternaria alternate are mostly common fungi allergens, sIgE detection of those two fungi are important for diagnosis of fungi induced allergic rhinitis and other respiratory diseases in people with different ages.