Catechin for the pharmacotherapy of chronic heart failure / 国际儿科学杂志

ABSTRACT

Heart failure is an end stage of the process of cardiovascular diseases.It is a condition of the heavy preload and afterload of heart,where it was associated with a progressive dysfunction of cardiac ejection.It can cause the systemic (pulmonary) congestion and the perfusion deficiency.For chronic heart failure in children,it could be resulted from some congenital and obtained heart diseases.The clinical pharmacotherapy strategy is mainly focused on the symptoms,yet which could not improve the prognosis and quality of life.Current studies have demonstrated catechins with a variety of physiological functions that may be responsible for clinically beneficial effects.It has been identified as a protective role in cardiovascular diseases with an unclear mechanism.Hence,this paper reviewed the mechanism of catechins in chronic heart failure in children.