Role of lncRNAs in accurate rejection after kidney transplantation / 国际外科学杂志

ABSTRACT

Kidney transplantation is the best treatment for end-stage renal disease.The types of the rejection can be divided into hyperacute rejection,accelerated rejection,acute rejection (AR) and chronic rejection according to the time of rejection after renal transplantation.Long noncoding RNAs (lncRNAs) play an important role in a variety of pathophysiological processes in the body,which can affect the stability of tissues.It is also closely related to various pathological processes such as acute kidney injury,glomerular disease and acute allograft rejection.What's more,the scholars found its huge potential for early diagnosis of AR after renal transplantation.This article will summarize the function of lncRNA in acute rejection of renal transplantation.