Branched chain amino acid transferase 1 and malignant tumors / 国际肿瘤学杂志
Journal of International Oncology
; (12): 36-39, 2019.
Article
in Zh
| WPRIM
| ID: wpr-743084
Responsible library:
WPRO
ABSTRACT
As a key enzyme that catalyzes the metabolism of branched chain amino acids,branched chain amino acid transferase 1(BCAT1)is often involved in a variety of biosynthetic pathways. Reaserches show that BCAT1 is highly expressed in many kinds of malignant tumors such as leukemia,glioma,nasopharyn-geal carcinoma,gastric cancer and breast cancer,et al,suggesting a close relationship with the proliferation, invasion and metastasis of tumor cells. Thus,BCAT1 plays an important role in the genesis and progression of tumor,and may have the potential to be a new therapeutic target.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Journal of International Oncology
Year:
2019
Type:
Article