Clinical Observations on Combined Use of Acupuncture and Medicine for Lower-limb Deep Venous Thrombosis / 上海针灸杂志

ABSTRACT

Objective To investigate the efficacy of acupuncture and moxibustion plus modern medication for lower-limb deep venous thrombosis. Method Ninety patients with lower-limb deep venous thrombosis were allocated, using a random number table, to control and observation groups. The control group received anticoagulant, thrombolytic and volume expansion therapy and the observation group, acupuncture and moxibustion in addition.Hemorheological indicators, D-dimer concentration and lower-limb venous blood flow velocity were measured before and after treatment. Result There were statistically significant pre/post-treatment differences in whole blood viscosity and platelet aggregation rate in the control group of patients after treatment (P<0.05). There were statistically significant pre/post-treatment differences in whole blood viscosity, plasma viscosity, hematocrit, erythrocyte electrodeposition rate and platelet aggregation rate in the observation group of patients after treatment (P<0.05). After treatment, there were statistically significant differences in whole blood viscosity, plasma viscosity, hematocrit, erythrocyte electrodeposition rate and platelet aggregation rate between the observation and control groups of patients (P<0.05). D-dimer concentration was lower in the control group of patients at the end of 10 and 20 days of treatment compared with before with astatistically significant difference (P<0.05). D-dimer concentration was lower in the observation group of patients at the end of 5, 10 and 20 days of treatment compared with before with a statistically significant difference (P<0.05). At the end of 5, 10 and 20 days of treatment, D-dimer concentration was lower in the observation group than in the control group with a statistically significant difference (P<0.05). At the end of treatment, there was a statistically significant pre-/post-treatment difference in color Doppler-visualized lower-limb blood flow velocity in both groups of patients (P<0.05). At the end of treatment, lower-limb blood flow velocity was higher in the observation group of patients than in the control group with a statistically significant difference (P<0.05). After treatment, the total efficacy rate was markedly higher in the observation group of patients than in the control group with a statistically significant difference (P<0.05). Conclusion Acupuncture and moxibustion plus modern medication is significantly more effective than medication alone in treating lower-limb deep venous thrombosis.