AnalysisofgenderdifferencesincoronaryarterydiseaseinpatientswithHIVinfectionbasedonCCTA / 实用放射学杂志

ABSTRACT

Objective Toanalyzethedifferencesofthecoronaryarterycalciumscore,andtheprevalence,severity,characteristics ofcoronaryarteryplaquesbetweenAIDSinfectedfemaleandmale.Methods 158AIDSpatients(72femalesand86 males)and102 HIVGuninfectedpatients(49femalesand53 males)withsuspectedcoronaryarterydiseaseinourhospitalwereenrolledbetween March2017andFebruary2018.Patientsunderwentcoronarycomputedtomographyangiography (CCTA)bythethirdgenerationdual sourceforceCT.Thedifferencesofcoronaryarteryplaquesbetweengenderswereassessed.Results In HIVGuninfectedpatients,the prevalenceoftotalplaque,mixedplaque,severestenosisandtwoGvesseldiseasewassignificantlyhigherinmalethanfemale(allP＜0.05) andtheprevalenceofnonGcalcifiedplaquewassignificantlylowerinmalethanfemale(allP＜0.05).InAIDSpatients,theprevalence oftotalplaque,calcifiedplaque,severestenosisandCACS＞100wassignificantlyhigherin malethanfemale(allP＜0.05)andthe prevalenceofnonGcalcifiedplaqueandmixedplaquesignificantlywaslowerinmalethanfemale(allP＜0.05).Theprevalenceofthree ormorevesselsdiseasein maleAIDSpatientswassignificantlyhigherthanfemaleAIDSpatients.Conclusion MaleAIDSpatients havehighercoronarycalcifiedscoreandheaviercoronaryatherosclerosisburdens.Inaddition,femaleAIDSpatientshavelesscoronary atherosclerosisburdens,butmixedplaqueseemtobemorefrequently.