Thediagnosticvalueof1.5T multiparametricMRIscoringsystemfordetecting earlyprostatecancerinthecentralglandarea / 实用放射学杂志

ABSTRACT

Objective Toevaluatethediagnosticvalueof1.5T multiparametricmagneticresonanceimaging (mpMRI)scoring systeminearlycentralprostatecancer(PCa).Methods DataofpatientswhoreceivedprostatempMRIfromJune2014toJune2016 wereanalyzedretrospectively.AccordingtoProstateImagingReportingandDataSystem Version2 (PIGRADS V2),a5Gscorescale wasadoptedandthetwoassociateradiologists,whowereblindedtoanyclinicaldetails,interpretedMRimages.Withthepathological resultsasthediagnosticgoldstandard,theROCcurvewasplottedandtheAUCwascalculated.Thediagnosticsensitivity,specificity, positivepredictivevalueandnegativepredictivevalue,accuracyofPCawerecalculatedunderdifferentdiagnosticthresholds(score3 or4).Results Atotalof41patientswereincludedinthestudyoutofwhich15caseswerethosewithPCaand26caseswithbenign prostatichyperplasia(BPH).TheAUCwas0.733(P＝0.014).Onthediagnosticthresholdscoreof3and4,thesensitivity,specificity, positivepredictivevalue,negativepredictivevalueandaccuracywere73.33%vs40%,61.54%vs92.31%,52.38%vs75%,80%vs 72.73%and65.85%vs73.17%respectively.Conclusion The1.5T mpMRIscoringsystemisrelativelyareliabletechniquefordetecting earlyPCainthecentralglandarea.PatientscanbefollowedGupwithprostatespecificantigen(PSA)whenthescoreislessthan3,and ascoreof4ormoreishighlysuggestiveofPCa.