Comparison of different drugs in the treatment of retinopathy caused by type 2 diabetes / 实用医学杂志

ABSTRACT

Objective Exploration of the efficacy of different drugs in the treatment of retinopathy caused by type 2 diabetes. Methods 120 type 2 diabetic retinopathy patients were randomly divided into treatment group of 60 patients and the control group of 60 patients based on random number table method, the control group were selected intravitreal injection with triamcinolone aetonide, and the treatment group were selected intravitreal injection with conbercept, all treatments were done three times and visual acuity, retinal and macular leakage of two groups were observed. Results The best corrected visual acuity after treatment in the treatment group and the control group were 40.45 ± 14.38 and 45.33 ± 12.89 respectively and that were significantly higher than the value before treatment, the statistically significant differences also happened between the two (P < 0.05). The CRT and TMV values of the two groups after treatment were significantly lower than that before treatment (P < 0.05) , while the CRT and TMV values in the treatment group were also significantly lower than the control group (P < 0.05). The typing leakage before and after treatment were mostly with diffuse and there were also no statistically significant differences in intra-group or inter-group. Conclusion Intravitreal injection of conbercept in the treatment of type 2 diabetic retinopathy can effectively recover vision and retinal conditions, it can stable patients' macular edema, thereby improve prognosis.